Cryptic crossword clue
Don that is head of staff gets tired 7

The most common and most likely answer to this crossword clue is the 7 letter word WEARIES

I've seen this crossword clue in The Daily Telegraph
W
E
A
R
I
E
S

Buddy explains!

The straight part
We know that "gets tired" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case gets tired = wearies.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does WEARIES mean?

WEARIES verb
  1. To make or to become weary.

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