Cryptic crossword clue
Dons’ home outside University College mess 4

The most common and most likely answer to this crossword clue is the 4 letter word MUCK

I've seen this crossword clue in Independent
M
U
C
K

Buddy explains!

The straight part
We know that "mess" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case mess = muck.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does MUCK mean?

MUCK noun
  1. (slimy) mud, sludge.
  2. Soft (or slimy) manure.
  3. Anything filthy or vile. Dirt; something that makes another thing dirty.
  4. Grub, slop, swill
  5. Money
  6. The pile of discarded cards.
MUCK verb
  1. To shovel muck.
  2. To manure with muck.
  3. To do a dirty job.
  4. To pass, to fold without showing one's cards, often done when a better hand has already been revealed.

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