Cryptic crossword clue
Doubter upset soccer tie-up 11

The most common and most likely answer to this crossword clue is the 11 letter word EUROSCEPTIC

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Buddy explains!

The straight part
We know that "Doubter" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case doubter = eurosceptic.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does EUROSCEPTIC mean?

EUROSCEPTIC noun
  1. One who is sceptical of European integration, such as the EEC, the EC, the EP, the EU, the Euro, etc.

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