The most common and most likely answer to this crossword clue is the 8 letter word SHUTDOWN
I've seen this crossword clue in The Daily Telegraph
S
H
U
T
D
O
W
N
More clues leading to the result SHUTDOWN
- Nuts who'd contrived closure of business?
- Nuclear power cut causes strike
- Failure appeared to embody small part of football team
- . Shed tears starting to see sad closure
- Turn off to open up? On the contrary
- Say, Pondicherry district in demonstration, to start non-cooperation against closure
- Drawn to melancholy, you need closure
Buddy explains!

The straight part
We know that "closure" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case closure = shutdown.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does SHUTDOWN mean?
SHUTDOWN noun- The action of stopping operations; a closing, of a computer, business, event, etc.
- A statement, insult, etc. that prevents the opponent from replying further.
- An autistic response to stress, etc. where the individual becomes silent and motionless.