Cryptic crossword clue
Dreadfully disables the securely settled 11

The most common and most likely answer to this crossword clue is the 11 letter word ESTABLISHED

E
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D

Buddy explains!

The straight part
We know that "securely settled" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case securely settled = established.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ESTABLISHED mean?

ESTABLISHED verb
  1. To make stable or firm; to confirm.
  2. To form; to found; to institute; to set up in business.
  3. To appoint or adopt, as officers, laws, regulations, guidelines, etc.; to enact; to ordain.
  4. To prove and cause to be accepted as true; to establish a fact; to demonstrate.
ESTABLISHED adjective
  1. Having been in existence for a long time and therefore recognized and generally accepted.
  2. Of a religion, church etc.: formally recognized by a state as being official within that area.
  3. (Model, procedure, disease) Explicitly defined, described or recognized as a reference.

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