Cryptic crossword clue
Drink

The most common and most likely answer to this crossword clue is the 4 letter word COKE

I've seen this crossword clue in The Guardian
C
O
K
E


Buddy explains!

The straight part
We know that "drugs" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case drugs = coke.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does COKE mean?

COKE noun
  1. Solid residue from roasting coal in a coke oven; used principally as a fuel and in the production of steel and formerly as a domestic fuel.
COKE verb
  1. To produce coke from coal.
  2. To turn into coke.
  3. To add deleterious carbon deposits as a byproduct of combustion.
COKE noun
  1. Cocaine.
COKE noun
  1. Cola-based soft drink.
  2. A bottle, glass or can of a cola-based soft drink.
  3. Any soft drink, regardless of type.

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