Cryptic crossword clue
Drink ruined a grocer at sea — he does have loads on his mind 10

The most common and most likely answer to this crossword clue is the 10 letter word SUPERCARGO

I've seen this crossword clue in The Guardian
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Buddy explains!

The straight part
We know that "at sea — he does have loads on his mind" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case at sea — he does have loads on his mind = supercargo.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does SUPERCARGO mean?

SUPERCARGO noun
  1. An officer on board a merchant ship who has charge of the cargo and its turnover (or the senior of two if one has two, the other being the subcargo; usually historical, since nowadays a person with such a job would remain on shore).

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