Cryptic crossword clue
Drive me crazy with a roast ham 13

The most common and most likely answer to this crossword clue is the 13 letter word OVERDRAMATISE

I've seen this crossword clue in Independent
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Buddy explains!

The straight part
We know that "ham" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case ham = overdramatise.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does OVERDRAMATISE mean?

OVERDRAMATISE verb
  1. To dramatize to excess; to make overdramatic.

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