Cryptic crossword clue
Drive to the north in PM being irritable 5

The most common and most likely answer to this crossword clue is the 5 letter word MARDY

M
A
R
D
Y

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The straight part
We know that "irritable" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case irritable = mardy.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does MARDY mean?

MARDY noun
  1. A sulky, whiny mood; a fit of petulance.
MARDY adjective
  1. Sulky or whining.
  2. Non-co-operative, bad-tempered or terse in communication.

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