Cryptic crossword clue
Drop litres in mouth before Christmas, when year’s out 7

The most common and most likely answer to this crossword clue is the 7 letter word GLOBULE

I've seen this crossword clue in The Times
G
L
O
B
U
L
E

Buddy explains!

The straight part
We know that "Drop" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case drop = globule.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does GLOBULE mean?

GLOBULE noun
  1. A small round particle of substance; a drop.

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