Cryptic crossword clue
Drug for soothing of French media worker 10

The most common and most likely answer to this crossword clue is the 10 letter word DEPRESSANT

I've seen this crossword clue in The Daily Telegraph
D
E
P
R
E
S
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A
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T

Buddy explains!

The straight part
We know that "Drug for soothing" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case drug for soothing = depressant.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does DEPRESSANT mean?

DEPRESSANT noun
  1. A pharmacological substance which decreases neuronal or physiological activity.
  2. An agent that inhibits the flotation of a mineral or minerals.
DEPRESSANT adjective
  1. (pharmaceutical effect) reducing functional or nervous activity.

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