Cryptic crossword clue
Drug has different form in the Orient 8

The most common and most likely answer to this crossword clue is the 8 letter word MORPHINE

M
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Buddy explains!

The straight part
We know that "Drug" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case drug = morphine.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does MORPHINE mean?

MORPHINE noun
  1. A crystalline alkaloid (7,8-didehydro-4,5-epoxy-17-methyl-morphinan-3,6-diol), extracted from opium, the salts of which are soluble in water and are used as analgesics, anaesthetics and sedatives; it is one of a group of morphine alkaloids.

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