Cryptic crossword clue
Drug satisfied husband in the morning, dear, keeping hard with a source of supply 15

The most common and most likely answer to this crossword clue is the 15 letter word METHAMPHETAMINE

I've seen this crossword clue in The Guardian
M
E
T
H
A
M
P
H
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T
A
M
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E

Buddy explains!

The straight part
We know that "Drug" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case drug = methamphetamine.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does METHAMPHETAMINE mean?

METHAMPHETAMINE noun
  1. A highly addictive phenethylamine stimulant drug, similar to cocaine. Its systematic (IUPAC) name is (S)-N-methyl-1-phenylpropan-2-amine.

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