The most common and most likely answer to this crossword clue is the 6 letter word LOADED
I've seen this crossword clue in The Daily Telegraph
L
O
A
D
E
D
Buddy explains!
The straight part
We know that "Drunk/prepared to be fired" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case drunk/prepared to be fired = loaded.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does LOADED mean?
LOADED verb- To put a load on or in (a means of conveyance or a place of storage).
- To place in or on a conveyance or a place of storage.
- To put a load on something.
- To receive a load.
- To be placed into storage or conveyance.
- To fill (a firearm or artillery) with munition.
- To insert (an item or items) into an apparatus so as to ready it for operation, such as a reel of film into a camera, sheets of paper into a printer etc.
- To fill (an apparatus) with raw material.
- To be put into use in an apparatus.
- To read (data or a program) from a storage medium into computer memory.
- To transfer from a storage medium into computer memory.
- To put runners on first, second and third bases
- To tamper with so as to produce a biased outcome.
- To ask or adapt a question so that it will be more likely to be answered in a certain way.
- To encumber with something negative, to place as an encumbrance.
- To provide in abundance.
- To weight (a cane, whip, etc.) with lead or similar.
- To adulterate or drug.
- To magnetize.
- Burdened by some heavy load; packed.
- (of a projectile weapon) Having a live round of ammunition in the chamber.
- Possessing great wealth.
- Drunk.
- Pertaining to a situation where there is a runner at each of the three bases.
- (also used figuratively) a die or dice being weighted asymmetrically, and so biased to produce predictable throws.
- (of a question) Designed to produce a predictable answer, or to lay a trap.
- (of a word or phrase) Having strong connotations that colour the literal meaning and are likely to provoke an emotional response. Sometimes used loosely to describe a word that simply has many different meanings.
- (of an item offered for sale, especially an automobile) Equipped with numerous options.
- Covered with a topping or toppings.
- Weighted with lead or similar.