The most common and most likely answer to this crossword clue is the 8 letter word DETESTED
I've seen this crossword clue in The Times
D
E
T
E
S
T
E
D
More clues leading to the result DETESTED
- Drunken employee originally breathalysed, perhaps couldn't stand
- Hated criterion being included in Act
- Couldn’t stand trial after returning newspaper boss starts to expose duplicity
- Hated activity being interrupted by assessment
- Hated action taken about evaluation
- Loathsome act surrounding trial
- Legal document about trial regarded as awful
- Couldn’t stand trial, caught in the act
- Try to get in the act, though very unpopular
- . Unpopular act involving tax
Buddy explains!

The straight part
We know that "couldn't stand" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case couldn't stand = detested.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does DETESTED mean?
DETESTED verb- To dislike intensely; to loathe.
- To witness against; to denounce; to condemn.