Cryptic crossword clue
Drunkenly outspoken, narcissistic creature in the main 9

The most common and most likely answer to this crossword clue is the 9 letter word SHELLFISH

I've seen this crossword clue in The Guardian
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Buddy explains!

The straight part
We know that "creature in the main" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case creature in the main = shellfish.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does SHELLFISH mean?

SHELLFISH noun
  1. An aquatic invertebrate having a shell, such as a mollusc or crustacean, especially when edible.

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