Cryptic crossword clue
Dull chemist in diffic­ulty penning article 11

The most common and most likely answer to this crossword clue is the 11 letter word MATHEMATICS

I've seen this crossword clue in The Guardian
M
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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does MATHEMATICS mean?

MATHEMATICS noun
  1. An abstract representational system used in the study of numbers, shapes, structure, change and the relationships between these concepts.
  2. A person's ability to count, calculate, and use different systems of mathematics at differing levels.

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