Cryptic crossword clue
Dull work may come to an end 8

The most common and most likely answer to this crossword clue is the 8 letter word FLATLINE

I've seen this crossword clue in The Guardian
F
L
A
T
L
I
N
E

Buddy explains!

The straight part
We know that "come to an end" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case come to an end = flatline.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does FLATLINE mean?

FLATLINE noun
  1. An unchanging state, as indicated in a graph of a variable over time.
  2. Asystole; the absence of heart contractions or brain waves.
FLATLINE verb
  1. (of the heart) To stop beating.
  2. (by extension) To die.
  3. To kill.
  4. To stay at the same level, without development; or, to fall.

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