The most common and most likely answer to this crossword clue is the 5 letter word DWEEB
I've seen this crossword clue in The Times
D
W
E
E
B
More clues leading to the result DWEEB
- Inadequate person finally found new life, some job
- Dumbo: Disney’s brainchild initially bringing in little?
- One royal society girl hugs is a nerd
- American jerk seeing worker maybe with daughter, bowled over
- Jerk knocking insect on hollow wood over
- Foreign weed given to British fool
- Geek to go on date with bachelor
- Level of noise overwhelms little nerd
- Dead small and born a fool
- Nerd starts to doubt whether erudition excites babes
Buddy explains!

The straight part
We know that "Dumbo" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case dumbo = dweeb.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does DWEEB mean?
DWEEB noun- (originally college slang) A boring, studious, or socially inept person.