Cryptic crossword clue
During this action one may have a change of heart 5,10

The most common and most likely answer to this crossword clue is the 5 plus 10 letter word ORGAN TRANSPLANT

I've seen this crossword clue in The Daily Telegraph
O
R
G
A
N
T
R
A
N
S
P
L
A
N
T

Buddy explains!

The straight part
We know that "this action" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case this action = organ transplant.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

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