Cryptic crossword clue
Dyer’s work around America is holding up 10

The most common and most likely answer to this crossword clue is the 10 letter word SUSTAINING

I've seen this crossword clue in The Guardian
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Buddy explains!

The straight part
We know that "holding up" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case holding up = sustaining.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does SUSTAINING mean?

SUSTAINING verb
  1. To maintain, or keep in existence.
  2. To provide for or nourish.
  3. To encourage or sanction (something).
  4. To experience or suffer (an injury, etc.).
  5. To confirm, prove, or corroborate; to uphold.
  6. To keep from falling; to bear; to uphold; to support.
  7. To aid, comfort, or relieve; to vindicate.
SUSTAINING noun
  1. The process by which something is sustained or upheld.
SUSTAINING adjective
  1. That sustains, supports or provides sustenance.

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