The most common and most likely answer to this crossword clue is the 6 letter word DOTCOM
D
O
T
C
O
M
More clues leading to the result DOTCOM
- High tech company lifts atmosphere around court
- Electronic concern when reverse circuit terminals in ruin
- Bardot comedy about an online business?
- On-line business boss bringing in nothing after October is upset
- Internet company‘s ruin, accepting tick, oddly
- E.g. Facebook stock regularly ignored in catastrophe
- Part of email address of commissioner Dorothy to start with
Buddy explains!

The straight part
We know that "E.g. Facebook" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case e.g. facebook = dotcom.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does DOTCOM mean?
DOTCOM noun- A company whose business is based around a website or primarily via the Internet.
- To convert to using or being based on e-commerce.