The most common and most likely answer to this crossword clue is the 8 letter word HEADACHE
I've seen this crossword clue in The Times
H
E
A
D
A
C
H
E
More clues leading to the result HEADACHE
- Passion killer that’s a cause of problems
- Each had awful athlete’s foot and pain at the other end
- Teacher with a cold: he gets this?
- Something that can stop one having sex is a problem
- Worry when lads race them endlessly
- Laugh about publicity account problem
- Worry I’m amused about a scoundrel getting upset
- Lead, one keeping hot, causes problem
- A bounder stood up amid laughter – why no sex tonight?
- Problem for leader to meet a revolutionary
Buddy explains!
The straight part
We know that "pain at the other end" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case pain at the other end = headache.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does HEADACHE mean?
HEADACHE noun- A pain or ache in the head.
- A nuisance or unpleasant problem.