Cryptic crossword clue
Eccentric dating serene actresses 12

The most common and most likely answer to this crossword clue is the 12 letter word TRAGEDIENNES

T
R
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G
E
D
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E
N
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Buddy explains!

The straight part
We know that "actresses" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case actresses = tragediennes.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does TRAGEDIENNES mean?

TRAGEDIENNES noun
  1. A female tragedian; a woman who acts in tragic drama

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