The most common and most likely answer to this crossword clue is the 1 plus 4 plus 2 plus 2 plus 5 letter word I WANT TO BE ALONE
I've seen this crossword clue in Independent
I
W
A
N
T
T
O
B
E
A
L
O
N
E
Buddy explains!
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.