The most common and most likely answer to this crossword clue is the 12 letter word SPIRITUALISE
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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does SPIRITUALISE mean?
SPIRITUALISE verb- To make spiritual; to invoke spirituality.
- To refine intellectually or morally; to purify from the corrupting influence of the world; to give a spiritual character or tendency to.
- To give a spiritual meaning to; to take in a spiritual sense; opposed to literalize.
- To extract spirit.
- To convert into, or impregnate with, spirit.