Cryptic crossword clue
Endangered? Holler and head off to save your skin 9,5

The most common and most likely answer to this crossword clue is the 9 plus 5 letter word VANISHING CREAM

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Buddy explains!

The straight part
We know that "to save your skin" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case to save your skin = vanishing cream.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

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