Cryptic crossword clue
Endeavour, perhaps, to get an A for each English subject 6

The most common and most likely answer to this crossword clue is the 6 letter word VASSAL

I've seen this crossword clue in The Daily Telegraph
V
A
S
S
A
L


Buddy explains!

The straight part
We know that "subject" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case subject = vassal.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does VASSAL mean?

VASSAL noun
  1. The grantee of a fief, feud, or fee; one who keeps land of a superior, and who vows fidelity and homage to him, normally a lord of a manor; a feudatory; a feudal tenant.
  2. A subordinate
VASSAL verb
  1. To treat as a vassal or to reduce to the position of a vassal; to subject to control; to enslave.
  2. To subordinate to someone or something.
VASSAL adjective
  1. Resembling a vassal; slavish; servile.

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