Cryptic crossword clue
Engendering invasion by America of constituent state 6

The most common and most likely answer to this crossword clue is the 6 letter word CAUSAL

I've seen this crossword clue in The Guardian
C
A
U
S
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Buddy explains!

The straight part
We know that "Engendering" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case engendering = causal.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does CAUSAL mean?

CAUSAL noun
  1. (grammar) a word (such as because) that expresses a reason or a cause
CAUSAL adjective
  1. Of, relating to, or being a cause of something; causing

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