Cryptic crossword clue
English doctor cut into cardinal, say, and effected cure

The most common and most likely answer to this crossword clue is the 8 letter word REMEDIED

I've seen this crossword clue in The Guardian
R
E
M
E
D
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D

Buddy explains!

The straight part
We know that "effected cure" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case effected cure = remedied.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does REMEDIED mean?

REMEDIED verb
  1. To provide or serve as a remedy for.

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