Cryptic crossword clue
Enterprise’s opening quarter ridden with frequent losses 7

The most common and most likely answer to this crossword clue is the 7 letter word VENTURE

V
E
N
T
U
R
E


Buddy explains!

The straight part
We know that "Enterprise" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case enterprise = venture.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does VENTURE mean?

VENTURE noun
  1. A risky or daring undertaking or journey.
  2. An event that is not, or cannot be, foreseen.
  3. The thing risked; especially, something sent to sea in trade.
VENTURE verb
  1. To undertake a risky or daring journey.
  2. To risk or offer.
  3. To dare to engage in; to attempt without any certainty of success. Used with at or on
  4. To put or send on a venture or chance.
  5. To confide in; to rely on; to trust.
  6. To say something.

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