Cryptic crossword clue
Enterprising set manoeuvred craftily 13

The most common and most likely answer to this crossword clue is the 13 letter word ADVENTURESOME

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Buddy explains!

The straight part
We know that "Enterprising" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case enterprising = adventuresome.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ADVENTURESOME mean?

ADVENTURESOME adjective
  1. Prone to, or willing to undertake, adventures; daring or bold.

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