Cryptic crossword clue
Enzyme offers control, containing nitrogen 5

The most common and most likely answer to this crossword clue is the 5 letter word RENIN

R
E
N
I
N


Buddy explains!

The straight part
We know that "Enzyme" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case enzyme = renin.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does RENIN mean?

RENIN noun
  1. A circulating enzyme released by mammalian kidneys that converts angiotensinogen to angiotensin-I. Because its activity ultimately leads to formation of angiotensin-II and aldosterone, this hormone plays a role in maintaining blood pressure.

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