Cryptic crossword clue
Ephemeral nature of rotting nectarines

The most common and most likely answer to this crossword clue is the 10 letter word TRANSIENCE

I've seen this crossword clue in The Guardian
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Buddy explains!

The straight part
We know that "Ephemeral nature" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case ephemeral nature = transience.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does TRANSIENCE mean?

TRANSIENCE noun
  1. The quality of being transient, temporary, brief or fleeting.
  2. An impermanence that suggests the inevitability of ending or dying.

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