The most common and most likely answer to this crossword clue is the 7 plus 6 letter word GREATLY MISSED
G
R
E
A
T
L
Y
M
I
S
S
E
D
Buddy explains!
The straight part
We know that "Epitaph" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case epitaph = greatly missed.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.