The most common and most likely answer to this crossword clue is the 3 plus 3 plus 3 plus 3 plus 5 letter word WHO ATE ALL THE PIES?
I've seen this crossword clue in The Guardian
W
H
O
A
T
E
A
L
L
T
H
E
P
I
E
S
?
Buddy explains!
The straight part
We know that "subject of this enquiry" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case subject of this enquiry = who ate all the pies?.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.