Cryptic crossword clue
Escape home beset by delay, very good for losing temperature 12

The most common and most likely answer to this crossword clue is the 12 letter word DEFERVESCING

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Buddy explains!

The straight part
We know that "losing temperature" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case losing temperature = defervescing.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does DEFERVESCING mean?

DEFERVESCING verb
  1. To experience an abatement or resolution of fever.
  2. To become less agitated; to cool down.

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