Cryptic crossword clue
Escorted northwards over river to expel parasites 7

The most common and most likely answer to this crossword clue is the 7 letter word DELOUSE

I've seen this crossword clue in The Daily Telegraph
D
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L
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Buddy explains!

The straight part
We know that "to expel parasites" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case to expel parasites = delouse.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does DELOUSE mean?

DELOUSE verb
  1. To remove lice from.
  2. To apply insecticides or insect repellents to, in order to be sure that no lice or other parasites are present.
  3. To remove malicious software, such as viruses, trojans, spyware, or worms, from.

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