Cryptic crossword clue
Essential for eg backbone of some companies: solid backing 6

The most common and most likely answer to this crossword clue is the 6 letter word OSSEIN

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Buddy explains!

The straight part
We know that "Essential for eg backbone" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case essential for eg backbone = ossein.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does OSSEIN mean?

OSSEIN noun
  1. The collagen component of bone

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