Cryptic crossword clue
Established Pole, losing head, has taken harmful amount neat 8

The most common and most likely answer to this crossword clue is the 8 letter word ORTHODOX

I've seen this crossword clue in The Times
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Buddy explains!

The straight part
We know that "Established" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case established = orthodox.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ORTHODOX mean?

ORTHODOX adjective
  1. Conforming to the accepted, established, or traditional doctrines of a given faith, religion, or ideology.
  2. Adhering to whatever is customary, traditional, or generally accepted.
  3. Of pollen, seed, or spores: viable for a long time; viable when dried to low moisture content.

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