Cryptic crossword clue
Everyman – so healthy! – knocked back enormous quantity of booze 10

The most common and most likely answer to this crossword clue is the 10 letter word METHUSELAH

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Buddy explains!

The straight part
We know that "enormous quantity of booze" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case enormous quantity of booze = methuselah.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does METHUSELAH mean?

METHUSELAH noun
  1. A wine bottle having the capacity of eight standard bottles (six litres)

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