The most common and most likely answer to this crossword clue is the 6 letter word CONDOM
I've seen this crossword clue in The Guardian
C
O
N
D
O
M
More clues leading to the result CONDOM
Buddy explains!

The straight part
We know that "some protection" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case some protection = condom.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does CONDOM mean?
CONDOM noun- A flexible sleeve made of latex or other impermeable material such as sheepskin, worn over an erect penis during intercourse as a contraceptive or as a way to prevent the spread of STDs.