Cryptic crossword clue
Excess marks off fellows that some find hard to digest 6

The most common and most likely answer to this crossword clue is the 6 letter word GLUTEN

G
L
U
T
E
N


Buddy explains!

The straight part
We know that "some find hard to digest" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case some find hard to digest = gluten.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does GLUTEN mean?

GLUTEN noun
  1. Fibrin (formerly considered as one of the "animal humours").
  2. Any gluey, sticky substance.
  3. The major protein in cereal grains, especially wheat; responsible for the elasticity in dough and the structure in baked bread.
  4. A gluey, sticky mass of clay, bitumen etc.

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