Cryptic crossword clue
Express contempt over first couple of errors, and depart 6

The most common and most likely answer to this crossword clue is the 6 letter word PERISH

P
E
R
I
S
H


Buddy explains!

The straight part
We know that "depart" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case depart = perish.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does PERISH mean?

PERISH verb
  1. To decay and disappear; to waste away to nothing.
  2. To decay in such a way that it can't be used for its original purpose
  3. To die; to cease to live.
  4. To cause to perish.

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