Cryptic crossword clue
Expresses disdain for southern Republican involved in fraudulent activities 6

The most common and most likely answer to this crossword clue is the 6 letter word SCORNS

I've seen this crossword clue in Independent
S
C
O
R
N
S

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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does SCORNS mean?

SCORNS verb
  1. To feel or display contempt or disdain for something or somebody; to despise.
  2. To reject, turn down.
  3. To refuse to do something, as beneath oneself.
  4. To scoff, to express contempt.

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