Cryptic crossword clue
Extremely hearty, rounded-up alien is transparent 7

The most common and most likely answer to this crossword clue is the 7 letter word HYALINE

H
Y
A
L
I
N
E

Buddy explains!

The straight part
We know that "is transparent" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case is transparent = hyaline.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does HYALINE mean?

HYALINE noun
  1. Anything glassy, translucent or transparent; the sea or sky.
  2. A clear translucent substance in tissues.
  3. The main constituent of the walls of hydatid cysts; a nitrogenous body, which, by decomposition, yields a dextrogyrate sugar, susceptible to alcoholic fermentation.
HYALINE adjective
  1. Glassy, transparent; amorphous.

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