The most common and most likely answer to this crossword clue is the 6 letter word THONGS
I've seen this crossword clue in The Guardian
T
H
O
N
G
S
Buddy explains!

The straight part
We know that "made of leather?" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case made of leather? = thongs.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does THONGS mean?
THONGS noun- A strip of leather.
- (usually in the plural) An item of footwear, usually of rubber, secured by two straps which join to pass between the big toe and its neighbour.
- An undergarment or swimwear consisting of very narrow strips designed to cover just the genitals and nothing more.
- The largest section of a bullwhip constructed of many straps of braided leather.