Cryptic crossword clue
Fail to observe Poe character in short story 10

The most common and most likely answer to this crossword clue is the 10 letter word CONTRAVENE

I've seen this crossword clue in The Guardian
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Buddy explains!

The straight part
We know that "Fail to observe" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case fail to observe = contravene.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does CONTRAVENE mean?

CONTRAVENE verb
  1. To act contrary to an order; to fail to conform to a regulation or obligation.
  2. To deny the truth of something.

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