Cryptic crossword clue
Family tree’s first thing to be filled by brewer? 6

The most common and most likely answer to this crossword clue is the 6 letter word FIRKIN

I've seen this crossword clue in Independent
F
I
R
K
I
N

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What does FIRKIN mean?

FIRKIN noun
  1. A varying measure of capacity, usually being a quarter of a barrel; specifically, a measure equal to nine imperial gallons.
  2. A small wooden vessel or cask of indeterminate size, used for butter, lard, etc.
  3. A weight measure for butter, equalling 56 pounds.

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