Cryptic crossword clue
Fancy woman sacrificing main artery to put weight on! 6

The most common and most likely answer to this crossword clue is the 6 letter word STRESS

I've seen this crossword clue in The Times
S
T
R
E
S
S


Buddy explains!

The straight part
We know that "to put weight on!" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case to put weight on! = stress.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does STRESS mean?

STRESS noun
  1. (Cause of) discomfort.
  2. Serious danger.
  3. An aversive state of stress to which a person cannot fully adapt.
  4. A seizing of property without legal process to force payment of a debt.
  5. The thing taken by distraining; that which is seized to procure satisfaction.
STRESS noun
  1. A physical, chemical, infective agent aggressing an organism.
  2. Aggression toward an organism resulting in a response in an attempt to restore previous conditions.
  3. The internal distribution of force across a small boundary per unit area of that boundary (pressure) within a body. It causes strain or deformation and is typically symbolised by σ or τ.
  4. Force externally applied to a body which cause internal stress within the body.
  5. Emotional pressure suffered by a human being or other animal.
  6. The emphasis placed on a syllable of a word.
  7. Emphasis placed on words in speaking.
  8. Emphasis placed on a particular point in an argument or discussion (whether spoken or written).
  9. Distress; the act of distraining; also, the thing distrained.
STRESS verb
  1. To apply force to (a body or structure) causing strain.
  2. To apply emotional pressure to (a person or animal).
  3. To suffer stress; to worry or be agitated.
  4. To emphasise (a syllable of a word).
  5. To emphasise (words in speaking).
  6. To emphasise (a point) in an argument or discussion.

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